Wednesday, March 31, 2010

The FDA and advertizing content

Open a newspaper or a magazine, sit down to watch the television and you are guaranteed to find an advert for an erectile dysfunction (ED) drug. It's like clockwork and confirms the underlying reality. The market for a treatment for ED is worth billions of dollars a year. More importantly, as the male population ages, the incidence of ED rises. It's one of those facts of life. Older men have more problems. Given the crest of the baby boom is still a few years away, the estimate is that, come 2025, there will be 300 million men in the US wanting treatment for ED. If you think the scramble to maintain brand recognition is tough now. You wait for the next fifteen years to unravel. It's going to get really brutal as all the manufacturers fight for a slice of the pie.

Which leads us to the thorny question of the controls over what the advertizers can say about their product. Let's start with the time of day. Many parents have been distressed that the adverts air on television during the afternoon and early evening when their children are watching. This leads to embarrassing moments as these naturally curious youngsters ask their parents to explain what erections are. As it stands, there are no formal limits on when these adverts can air. It's for the television stations to make editorial decisions. After all, everyone is in this business for the money so, if you have a vacant slot on a show to sell, you usually take the money from an advertizer no matter what is for sale. That's capitalism for you. Significantly, all the cost of this pharmaceutical advertizing is tax deductible. So, guess what. All the advertizing dollars get added to the price of the drugs you buy and this adds to the overall cost of healthcare. If the Administration is serious about cutting health costs, all it has to do is ban television advertising and, overnight, the cost of the drugs drops.

So when the television ads air, what exactly do we see and hear. The standard slots vary between 40 and 60 seconds in length. The images are usually of couples doing things together. They may be walking hand-in-hand along a beach, riding bicycles or doing some work in the yard. It's not considered appropriate to show real people in flagrante delicto. They must be caught in romantic moments suggesting the possibility of sexual activity later - assuming they are not too tired after digging up the yard. But the words list all the side effects and then mention how great viagra is as a treatment for ED. The FDA regulates pharmaceutical ads and requires the content to show "fair balance". So what you hear is written by lawyers trying to avoid sanctions imposed by the FDA. In other words, "fair balance" means telling the consumer about both the benefits and the risks of each drug. It's not too alarming to hear you may get a headache if you buy viagra. Some of the other drugs, say for treating rheumatism, list fatal side effects. So let's keep this particular sales pitch simple. Viagra is the best of the ED drugs and it gets great results almost every time.
Let's Go....

The Mayo Clinic is using Tramadol before and after surgery

Confidence is a strange creature. It lives somewhere deep in the woods of all our fears and insecurities, and only emerges when we are absolutely certain everything is going to be alright. So, when it comes to the idea of surgery, where some surgeon is going to be standing over us with his or her arms inside our bodies with a saw, most of us prefer total unconsciousness from well before the operation until well after it. No-one in the West would accept the practice of acupuncture where, with a few needles sticking in our head and left big toe, we are able to chat with the surgeon about the latest episode of "Lost". General anesthetic is the desired norm. For some reason, our culture prefers to protect the mind from all conscious knowledge of what is going on during the procedure and from the pain caused by the surgery. The latter is usually produced by the intravenous administration of one of the strongest painkillers. The problem with this approach is that the combination of general anesthesia with intravenous drugs is most likely to produce nausea and vomiting. If the use of painkillers goes on for any length of time, it also causes the bowels to slow down and grow uncomfortable.

For the last ten years, the Mayo Clinic has been pioneering a different approach for hip or knee replacement surgery. Rather than simply knocking people out, surgeons now start by administering painkillers for a day or more before the operation. Using pills to build up the concentration of painkiller in the blood stream before the operation has two beneficial effects: patients feel less pain during the surgery and have none of the side effects associated with intravenous administration after surgery. Secondly, the patients are given sedatives before the operation. This calms the mind and reduces the need for a general anesthetic. Indeed, most surgery is now performed either using a nerve block which numbs the immediate area around the hip or knee joint, or regional anesthetic which only affects the lower half of the body. The majority of patients report less pain following localized anesthetic and only require the use of milder painkillers like tramadol during the recovery phase. People are also able to regain mobility more quickly, getting out of bed one or two days earlier than following a general anesthetic. This approach also expands the number of people able to undergo surgery. Many people who are either overweight or older are refused general anesthetic because their breathing or heart action is weak.

In some senses, this is dramatic news. Instead of that awful feeling of disorientation and nausea following a general anesthetic, people are recovering faster and going into physical therapy earlier to get their limbs moving again. This is a significant improvement. Indeed, just consider the difference in the choice of painkillers. Under the old protocol, the strongest painkillers would be administered intravenously. Today, people are going through the whole procedure and only buy tramadol. This is not to deny the use of the stronger opiate drugs. But it gives patients a choice and avoids any potential problems with dependence. Whether this new approach will roll out across the whole of the hospital service is speculative. People can be talked into this because they have greater confidence in the Mayo Clinic. Whether their confidence will be so high in a local hospital is more difficult to predict. All we can say is that fear of pain is a big motivator.
Let's Go....

Chronic heart failure isn't something that restricts you from having sex

The recent study the results of which were published in the Fears that men Mayo Clinic Proceedings journal has concluded that chronic heart failure in men is not a fatal condition that bans sex life once and for all, and men with this disease can still enjoy intimacy and use drugs ED drugs to help them boost sexual performance if being under close medical attention and supervision.

The researchers running the whole project, Stacy Mandras and Mandeep Mehra, have undertaken a detailed analysis comprising the results of other researches that studied sexual activity in men who were suffering from coronary artery disease. The results of such an analysis have surprised them, showing that men with such a condition and without it had the same levels of increase in heart rate, vessel tension and respiratory rate that were all within safe limits. In fact, the highest hear rate reported in the study while a man was having sex was lower than a daily maximum achieved during simple everyday activities.

The studies have also included patients with chronic heart failure who also suffered from erectile dysfunction. Erectile dysfunction usually takes place when there's not enough blood flowing into the penis for the man to be able to achieve erection. Drugs used for treating the problem such as Viagra or Levitra stimulate the blood flow into the penis and thus can make the problem even worse.

They have also taken into account the safety of such drugs in cases of congestive heart failure. Erectile dysfunction medications directly affect the blood flow and blood vessels and it would pose a great health risks if combined with other heart medications, leading to dramatic changes in blood pressure levels over a short period of time.

However, the studies have displayed that Viagra can be safely used in such patients taking heart medications only with the sole condition of being under strict medical supervision. There isn't sufficient data on how safe other ED drugs such as Levitra and Cialis are in such situations, but taking into account that they have quite the same pharmacological properties and mechanism of action one can assume that they are quite safe too.

Thus, the authors of this study conclude that it's safe form men with erectile dysfunction and mild to moderate chronic heart failure to buy Viagra and use it with the purpose of improving the quality of their erection, still with the condition of going through detailed screening before being prescribed with the drug.

Still there are people who cannot use such drugs, what's the solution for them? Health care specialists state that men can enjoy having active sexual life regardless of their age if following a healthy lifestyle and having regular physical activity. Erectile dysfunction can also be caused by certain medications that you are taking or even inappropriate nutrition. Take a closer look at your lifestyle and make the necessary improvements and you will see that the quality of your sexual life will be improved.
Let's Go....

Tuesday, March 30, 2010

The magnificent achievements of the best known ED drug

High Blood pressure treatment

Most of us know Sildenafil as the medicine that treats erectile dysfunction. Only few of us know that this drug can also treat angina and any other chest problems that may occur.

This medical substance is used for preventing or partially decreasing the rate of a chemical reaction - that chemical that could be found in some of the body parts, mainly where PDE is found. The blood pressure is the major obstacle to go through therefore the goal of the Sildenafil experience is to hit the arteries in the lungs as exactly the lungs should have the blood pressure decreased.

Many counties went on with the researches on Sildenafil, trying to figure out what other benefits it gives to people that take it. High Blood pressure treatment seemed to be one of those. The drug ended up being approved by the government and started to get manufactured under a completely different name - known as Revatio. The bets thing about it is that it only penetrates in the arteries where the high blood pressure exists and doesn't go though all the vascular system. Some kids are born with pulmonary arterial hypertension so there have been some cases when Sildenafil was given to kids for an experiment. The drug makes the blood circulate more actively running through the baby chest. But you have to remember that the dose should not be big as it is a child and their body is much different from an adult body. We have to warn you that the drug is only good when taken rationally as an overdose can create the health problems that have not been predicted before.

Sportsmen praise the drug.

You may never believe it or even find it funny to believe but many famous sportsmen have admitted that Sildenafil is very useful when it comes to making a great performance on the field. This fact has no FDA approval and there is no guarantee that it actually does magic in sports. We have a word of one of the widely renowned sportsmen such as Roger Clemens and others that are ready to confess all around the world how worthy Viagra is for sport result achievements. The good thing about the medication is that it is actually not considered to be an enhancing drug that can influence the body in the wrong way. It is just created to make the circulation better and that is not banned anyhow anywhere. The body gets much stronger and works much better with this drug. But of course, the dosage should be regular as getting a bigger does leads to unpredictable consequences.

A way of curing the high-altitude pulmonary edema

Some institutions claim that Viagra's dose may help you get on the path of recovery. When we talk about pulmonary edema - we get frightened, as the outcome of this malady can be as severe as death. But Sildenafil (generic viagra) can reduce the altitude and make the illness less harmful. Scientists from Nepal made this discovery not so long ago and they are now almost 100% sure that the drug lets the patients have the ability to absorb oxygen. For those people who need an urgent hospitalization it is the best salvation as sometimes patients happen to live far away and it take time to transport them to the hospital.

Now you know the magic tricks Sildenafil is capable of doing. I hope you know to use it when you have to!
Let's Go....

Is Cialis like an aphrodisiac ?

Whenever you start reading about erectile dysfunction, the first facts that leap off the screen are that this is a physical problem and, as such, there is a treatment or cure. Most of the explanations of why erections fail focus on different chemical messengers, and arteries dilating or contracting. It's like reading a description of a plumbing system - turn this valve, water pressure builds here, and so on. This type of explanation suits the pharmaceutical companies. If this chemical messenger is the problem, a drug that specifically targets it will solve the problem. Except human biology is not always so predictable. Let's start again. From the dawn of time, men have sometimes had difficulty in getting an erection hard enough to penetrate a woman. Out of frustration, they have looked around for solutions and, over time, a number of natural substances have emerged as aphrodisiacs. The lists vary from century to century and culture to culture. The substances work because the prevailing mythology predicts they will work. It may be the crushed horn of this animal added to food, or the blood of this animal notorious for its sexual prowess rubbed on to your penis. There are no common denominators. The process that produces the results takes place in the mind. These substances work because the mind believes in them strongly enough.

Starting this article again means making a simple statement. An erection is a response to sexual stimulation. If the mind does not find the activity stimulating, there will be no erection. As proof of this, we need go no further than the thousands of clinical trials for all major drugs on the market. The methods are consistent. You divide the participants into two groups. One gets the real drug. The other gets a placebo, i.e. a fake tablet that looks the same but is made out of chalk or some other inert substance. A placebo cannot have any physical effect but, on average, about one-third of all participants who are given the placebo report an improvement in their condition. They improve because the mind is strong enough to change the biology of the body.

Now we can say something real about a drug like cialis. This is the leading brand for the treatment of erectile dysfunction in many of the markets around the world. It's reputation is so great that it has even attracted the nickname of the "weekend pill", i.e. it produces thirty-six hours of sexual responsiveness. There is no doubt at all about the effectiveness of this drug. As a matter of chemistry, it does exactly what it's supposed to do. What completes its performance is the power of its reputation. When men take a drug which has such a good reputation, the chemical action is added to the placebo effect and, with mind and body working together, it produces the best results. Cialis is good and gets better because men believe in it. Now available in two forms, you can enjoy the benefits of this modern aphrodisiac as either the weekend pill, taken as needed, or in a once-daily form to give you an erection on demand whenever the opportunity arises.
Let's Go....
 

Enjoy Your Life Copyright © 2009 WoodMag is Designed by Ipietoon for Free Blogger Template